CyanoOmicsDB

CyanoOmicsDB aggregates genomic, transcriptomic, and proteomic data from 928 sequenced cyanobacterial genomes (over 8 million gene entries) to enable functional genomic analysis, gene expression profiling, and characterization of protein modifications.

Key Features:

• Extensive Gene Entries: Contains over 8 million entries representing genes from 928 cyanobacterial genomes.
• Comprehensive Functional Information: Provides multiple identifiers, genomic locations, and DNA sequences for each gene entry.
• Protein-Related Data: Includes predicted functions, amino acid sequences, homologs, protein-domain super-families, and accession numbers linked to public protein function databases.
• Transcriptional and Translational Profiles: Integrates transcriptional and translational profiles of Synechocystis sp. PCC 6803 across diverse environmental conditions and genetic backgrounds.
• Gene Transcription Start Sites: Catalogs 23,689 gene transcription start sites.
• Peptides and Post-Translational Modifications: Records 94,644 identified peptides and 16,778 post-translational modification sites from transcriptomes or proteomes of several model cyanobacteria.

Scientific Applications:

• Functional Genomics: Enables exploration of gene functions and interactions within cyanobacterial genomes.
• Gene Expression Studies: Supports analysis of gene expression responses using integrated transcriptional and translational datasets under varied environmental and genetic conditions.
• Protein Function Analysis: Facilitates studies of protein sequence, domain architecture, homologous relationships, and post-translational modifications.

Methodology:

Integrates and visualizes genomic, transcriptomic, and proteomic data and compiles information from multiple sources.