DATF

DATF catalogs 1,827 known and predicted transcription factors of Arabidopsis thaliana organized into 56 families, including 1,177 cloned sequences and associated 3D structure templates, EST expression data, transcription factor binding sites, and nuclear localization signals to support analysis of transcriptional regulation.

Key Features:

• Transcription Factor Catalog: Contains 1,827 known and predicted transcription factors from Arabidopsis thaliana organized into 56 distinct families.
• Cloned Sequences: Includes 1,177 cloned transcription factor sequences.
• 3D Structure Templates: Provides structural templates for transcription factors to inform molecular architecture and interaction analyses.
• EST Expression Information: Supplies Expressed Sequence Tag (EST) data indicating expression patterns across tissues and developmental stages.
• Transcription Factor Binding Sites: Contains information on transcription factor binding sites relevant to gene regulation.
• Nuclear Localization Signals: Provides details on nuclear localization signals for transcription factors.

Scientific Applications:

• Gene regulation research: Enables analysis of transcriptional regulatory mechanisms in Arabidopsis thaliana using TF sequences, binding sites, and expression data.
• Functional characterization: Supports functional studies of individual transcription factors using cloned sequences and structural templates.
• Transcriptional network analysis: Facilitates reconstruction and analysis of transcriptional networks by integrating binding site, EST expression, and localization data.
• Developmental and stress-response studies: Aids investigation of transcription factor roles in plant development and responses to stress.

Methodology:

Curation compiled and organized transcription factors into 56 families and aggregated cloned sequences, 3D structure templates, EST expression information, transcription factor binding sites, and nuclear localization signals.