DECIPHER

DECIPHER provides sequence analysis and management functions using Bioconductor packages in R to support genomics and molecular biology research.


Key Features:

  • Bioconductor integration: Implemented as part of the Bioconductor framework, enabling access to Bioconductor infrastructure and conventions.
  • Interoperability: Comprises 934 interoperable packages that enable integration of diverse bioinformatic and statistical methods.
  • R foundation: Built on the R statistical programming language for statistical computing and data visualization.
  • Community-driven contributions: Development and package contributions originate from a global scientific community.
  • Formal review and testing: Packages undergo formal initial review and continuous automated testing within Bioconductor.

Scientific Applications:

  • Genomics and molecular biology: Supports analysis and management of biological sequences for genomics and molecular biology studies.
  • High-throughput data analysis: Enables analysis of high-throughput genomic datasets.
  • Sequence alignment and annotation: Provides functionality for sequence alignment and annotation workflows.
  • Statistical modeling and visualization: Facilitates statistical modeling and visualization of genomic data using R.
  • Gene expression and variant analysis: Supports gene expression analysis and variant analysis tasks.

Methodology:

Integration of bioinformatics packages with R-based statistical techniques, leveraging interoperable Bioconductor packages; packages are subject to formal initial review and continuous automated testing.

Topics

Collections

Details

License:
GPL-3.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

Downloads

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