Delila-PY

Delila-PY leverages the Delila software suite to identify and analyze DNA binding motifs for elucidating regulatory mechanisms controlling gene expression.


Key Features:

  • Streamlined pipeline: Automates Delila-based analyses to perform motif prediction from DNA sequence inputs.
  • Integration with Delila Suite: Executes algorithms from the Delila software suite to identify and analyze DNA binding motifs.
  • Flexibility and Control: Provides configurable parameters to customize motif discovery and analysis workflows.

Scientific Applications:

  • Motif prediction: Predicts potential DNA binding motifs to elucidate regulatory mechanisms.
  • Gene expression studies: Identifies binding sites and associated motifs to inform analyses of transcriptional regulation across organisms.

Methodology:

Uses algorithms from the Delila software suite to analyze DNA sequences and predict DNA binding motifs, with the pipeline automating these algorithmic steps.

Topics

Details

Tool Type:
command-line tool
Programming Languages:
C, Python
Added:
9/8/2021
Last Updated:
9/13/2021

Operations

Publications

Myers KS, Place M, Kominek J, Noguera DR, Donohue TJ. Delila-PY, a Pipeline for Utilizing the Delila Suite of Software to Identify Potential DNA Binding Motifs. Microbiology Resource Announcements. 2021;10(15). doi:10.1128/mra.00160-21. PMID:33858925. PMCID:PMC8050967.

PMID: 33858925
PMCID: PMC8050967
Funding: - U.S. Department of Energy: DE-SC0018409

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