DEVEA

DEVEA performs differential expression analysis, data visualization, and enrichment/pathway analysis of transcriptomics (RNA-Seq) data.


Key Features:

  • Differential Expression Analysis: Performs statistical identification of genes with significant expression changes between experimental groups using transcriptomics data.
  • Data Visualization: Produces plots and tabular summaries for exploration of gene expression profiles and statistical comparisons across conditions.
  • Enrichment Pathway Analysis: Conducts enrichment analysis to identify biological pathways associated with differentially expressed genes.
  • Flexible Data Input: Accepts transcriptomics datasets and gene lists with or without associated statistical values.
  • Comprehensive Reporting: Generates customizable HTML reports that summarize analysis results and outputs.

Scientific Applications:

  • Gene expression studies: Analysis of RNA-Seq data to detect expression changes associated with disease states, developmental stages, or environmental responses.

Methodology:

The workflow integrates data input and preprocessing, statistical (differential expression) analysis, enrichment/pathway analysis, and visualization within an R Shiny framework.

Topics

Details

License:
Apache-2.0
Tool Type:
web application
Programming Languages:
R
Added:
8/8/2023
Last Updated:
11/24/2024

Operations

Publications

Riquelme-Perez M, Perez-Sanz F, Deleuze J, Escartin C, Bonnet E, Brohard S. DEVEA: an interactive shiny application for Differential Expression analysis, data Visualization and Enrichment Analysis of transcriptomics data. F1000Research. 2023;11:711. doi:10.12688/f1000research.122949.2. PMID:36999088. PMCID:PMC10043628.

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