DEVEA
DEVEA performs differential expression analysis, data visualization, and enrichment/pathway analysis of transcriptomics (RNA-Seq) data.
Key Features:
- Differential Expression Analysis: Performs statistical identification of genes with significant expression changes between experimental groups using transcriptomics data.
- Data Visualization: Produces plots and tabular summaries for exploration of gene expression profiles and statistical comparisons across conditions.
- Enrichment Pathway Analysis: Conducts enrichment analysis to identify biological pathways associated with differentially expressed genes.
- Flexible Data Input: Accepts transcriptomics datasets and gene lists with or without associated statistical values.
- Comprehensive Reporting: Generates customizable HTML reports that summarize analysis results and outputs.
Scientific Applications:
- Gene expression studies: Analysis of RNA-Seq data to detect expression changes associated with disease states, developmental stages, or environmental responses.
Methodology:
The workflow integrates data input and preprocessing, statistical (differential expression) analysis, enrichment/pathway analysis, and visualization within an R Shiny framework.
Topics
Details
- License:
- Apache-2.0
- Tool Type:
- web application
- Programming Languages:
- R
- Added:
- 8/8/2023
- Last Updated:
- 11/24/2024
Operations
Publications
Riquelme-Perez M, Perez-Sanz F, Deleuze J, Escartin C, Bonnet E, Brohard S. DEVEA: an interactive shiny application for Differential Expression analysis, data Visualization and Enrichment Analysis of transcriptomics data. F1000Research. 2023;11:711. doi:10.12688/f1000research.122949.2. PMID:36999088. PMCID:PMC10043628.
Documentation
Training material
https://shiny.imib.es/DESeqDevea/tutorial.htmlTraining material
https://shiny.imib.es/simpleDevea/tutorial.htmlDownloads
Links
Repository
https://github.com/MiriamRiquelmeP/DEVEA