diffGeneAnalysis

diffGeneAnalysis performs microarray data analysis within the Bioconductor framework using the R programming language to identify differentially expressed genes.


Key Features:

  • Interoperability: Integrates with the Bioconductor ecosystem, including 934 interoperable packages, to enable combined workflows with other Bioconductor tools.
  • Open-source Development: Developed and maintained through community contributions within the Bioconductor project.
  • R-based Statistical Analysis: Implements microarray data processing and complex statistical analyses using the R programming language.

Scientific Applications:

  • Genomics Research: Identification and analysis of differentially expressed genes across conditions or treatments from microarray experiments.
  • Molecular Biology Studies: Examination of gene expression patterns to inform studies of gene regulation and function using microarray data.

Methodology:

Computations are implemented in the R programming language and packages undergo continuous automated testing within the Bioconductor framework.

Topics

Collections

Details

License:
GPL-3.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

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