DNAforge

DNAforge provides a unified interface to multiple design methods for DNA and RNA wireframe nanostructures, enabling the design, visualisation and sequence generation for highly complex wireframe nanostructures with a fully automated process.

Key Features:

• Multiple design methods for DNA nanostructures: Currently supports three distinct design methods for DNA nanostructures.
• Multiple design methods for RNA nanostructures: Currently supports two distinct design methods for RNA nanostructures.
• Extensible framework: Allows for the integration of additional design methods into the same unified framework.
• Sequence generation: Generates sequences for designed nucleic acid nanostructures.
• Visualisation: Provides visualisation capabilities for designed wireframe nanostructures.
• Fully automated process: Automates the complete design workflow for complex wireframe nanostructures.

Scientific Applications:

• DNA wireframe nanostructure design: Enables the design of highly complex DNA wireframe nanostructures using multiple supported methods.
• RNA wireframe nanostructure design: Enables the design of highly complex RNA wireframe nanostructures using multiple supported methods.

Methodology:

DNAforge implements a fully automated computational process that unifies several recent design methods for DNA and RNA wireframe nanostructures within a single framework.