DNannotator

DNannotator performs de novo annotation and integration of genomic features, including single nucleotide polymorphisms (SNPs), sequence-tagged sites (STSs), and exons, to support genomic data mining and high-throughput experiment design.

Key Features:

• De novo annotation: Performs de novo annotation of genomic regions targeting SNPs, STSs, and exons.
• Batch annotation: Accepts annotation source data such as SNPs, genes, primers, and specified genomic targets for batch processing of large datasets.
• Annotation migration: Migrates existing annotations in GenBank format from one sequence to another to accommodate sequence updates and different sequence versions for sequences less than 30 kilobases.
• Output formats: Produces results in GenBank format and tab-delimited text files for importation into databases or spreadsheets.
• Visualization compatibility: Generates outputs compatible with graphic viewers such as the Genome Browser and Artemis.
• Quality evaluation: Optionally provides reference data reports to evaluate the quality of annotations.

Scientific Applications:

• Gene and marker discovery: Support development of local discoveries such as genes and genetic markers from annotated genomic regions.
• Annotation integration: Facilitate collection and integration of annotations from multiple resources into a unified dataset.
• High-throughput experimental design: Enable design of high-throughput experiments based on integrated annotated genomic data.

Methodology:

Accepts user-defined or specified target data, performs de novo annotation of SNPs, STSs, and exons, and migrates existing GenBank annotations between sequences.