Doelan

Doelan performs automated quality control for DNA microarray production by executing validation tests on hybridizations and producing quality metrics.

Key Features:

• Automated Quality Control: Systematically executes a series of quality control tests on hybridizations to validate microarray chip batches.
• Plug-in Architecture: Modular plug-in system enables integration of custom or bespoke validation tests.
• Reporting and Quality Metrics: Generates detailed reports that provide insights into DNA microarray quality metrics and support quality certification workflows such as ISO 9001.
• Implementation: Java-based software implementation.
• License: Distributed under the GNU General Public License (GPL).

Scientific Applications:

• Production Quality Control: Routine validation of microarray production batches through automated hybridization testing.
• Reproducibility Assessment: Assessment of reliability and reproducibility of microarray data across batches.
• Standards Compliance: Facilitation of compliance with international quality standards such as ISO 9001.

Methodology:

Doelan executes predefined quality control tests on hybridizations performed during microarray production, and its plug-in system permits integration of additional user-defined validation tests.