DrEdGE
DrEdGE enables interactive visualization and exploration of RNA sequencing (RNAseq) data to facilitate discovery of differentially expressed genes, samples, and expression patterns.
Key Features:
- Interactive Data Visualization: Generates dynamic, customizable visual representations of RNA sequencing (RNAseq) data.
- Queryable Visualizations: Allows condition-based querying of visualizations to identify genes, samples, or expression patterns of interest.
- Public Dataset Integration: Supports creation of visualizations from public RNAseq datasets including human neuronal tissue, mouse embryonic tissue, and Caenorhabditis elegans whole embryos.
- Differential Expression Exploration: Facilitates examination and comparison of differential gene expression patterns across samples and conditions.
Scientific Applications:
- Differential gene expression analysis: Enables identification and visualization of differentially expressed genes from RNAseq datasets.
- Developmental biology: Supports exploration of temporal and tissue-specific expression patterns in embryonic datasets.
- Neurobiology: Facilitates visualization and comparison of gene expression in human neuronal tissue datasets.
- Evolutionary genetics: Allows comparative examination of expression patterns across species and developmental stages.
Methodology:
Generation of interactive, queryable visualizations from RNA sequencing (RNAseq) datasets.
Topics
Details
- Tool Type:
- web application
- Added:
- 1/18/2021
- Last Updated:
- 3/3/2021
Operations
Publications
Tintori SC, Golden P, Goldstein B. Differential Expression Gene Explorer (DrEdGE): a tool for generating interactive online visualizations of gene expression datasets. Bioinformatics. 2020;36(8):2581-2583. doi:10.1093/bioinformatics/btz972. PMID:31899488. PMCID:PMC7178403.
PMID: 31899488
PMCID: PMC7178403
Funding: - National Institutes of Health: R01 GM083071, R35 GM134838
- National Science Foundation: IOS 1557432
- Damon Runyon Cancer Research Foundation: 19-1211