DRESIS

DRESIS provides a comprehensive database of drug resistance information across diverse diseases, cataloging molecular mechanisms and clinically and experimentally verified resistance data to inform research and clinical practice.

Key Features:

• Comprehensive Coverage: DRESIS systematically catalogs all known molecular mechanisms underlying drug resistance, organized into six distinct mechanism types.
• Extensive Disease Range: DRESIS covers a broad range of diseases affected by drug resistance, extending beyond cancers and infections.
• Clinically and Experimentally Verified Data: DRESIS describes clinically and experimentally verified resistance data for a large number of drugs.

Scientific Applications:

• Drug Discovery: Provides detailed resistance landscapes to aid identification of potential targets for new therapeutic interventions.
• Clinical Treatment Optimization: Supplies clinically and experimentally verified resistance data to support tailoring of treatments and addressing resistance in patient care.
• Comparative Disease Analysis: Enables study and comparison of drug resistance mechanisms across a wide range of diseases beyond traditional focuses.

Methodology:

Systematic cataloging and annotation of molecular mechanisms and clinically and experimentally verified drug resistance data.