DrugRepV

DrugRepV provides a curated database of repurposed antiviral drugs with annotations to support antiviral drug discovery and repurposing against 23 viruses associated with epidemics or pandemics.

Key Features:

• Extensive Data Collection: The database contains 8,485 entries comprising 3,448 unique compounds tested for antiviral activity.
• Targeted Viral Coverage: Records cover 23 viruses known to cause epidemics or pandemics.
• Multifaceted Data Fields: Entries include fields for drugs, viruses, drug targets, clinical trials, and assays.
• Comprehensive Statistics: The resource provides aggregated statistics summarizing repurposed-candidate data.
• Integration with External Resources: Entries are hyperlinked to DrugBank, PubChem, NCBI-Taxonomy, ClinicalTrials.gov, and the World Health Organization for additional chemical, biological, and clinical information.

Scientific Applications:

• Repurposing research: Centralizes annotated repurposed-drug data to support researchers in virology, pharmacology, and related fields.
• Candidate prioritization for development: Supports identification and prioritization of promising repurposed candidates for further investigation or clinical trials.

Methodology:

Information was collated from existing literature on repurposed drugs tested for antiviral activity and organized into a structured database.