EaSeq

EaSeq provides an integrated computational environment for analysis and visualization of chromatin immunoprecipitation sequencing (ChIP-seq) data to support genome-wide exploration and hypothesis generation.

Key Features:

• Integrated computational environment: Integrates multiple analytical tools and supports analysis of both proprietary and public genome-wide datasets.
• Visualization of loci: Supports visualization of individual genomic loci and populations of loci, enabling inspection and selection of regions on plots.
• Extensive ChIP-seq toolset: Includes over 20 analysis tools specifically for ChIP-seq data to perform a wide range of analytical tasks.

Scientific Applications:

• Polycomb ChIP-seq meta-analysis: Facilitates meta-analysis of public Polycomb ChIP-seq data to screen large datasets for associations.
• Mouse embryonic stem cell screening: Has been used to analyze over 900 datasets from mouse embryonic stem cells to identify factors potentially associated with Polycomb recruitment.

Methodology:

Combines visualization capabilities with a suite of analytical tools to extract information and perform comprehensive meta-analyses of ChIP-seq datasets.