ecolitk

ecolitk provides visualization and analysis of Escherichia coli genomic data, focusing on circular genomes such as bacterial chromosomes and plasmids within the Bioconductor/R ecosystem.


Key Features:

  • Circular Genome Plotting: Provides plotting functions tailored for circular genomes to visualize genomic features on plasmids and bacterial chromosomes.
  • Interoperability with Bioconductor Packages: Integrates with the Bioconductor ecosystem (934 interoperable packages) to enable data manipulation, analysis, and visualization in R.
  • Formal Review and Automated Testing: Operates within Bioconductor's formal package review process and continuous automated testing framework to ensure reproducibility and package reliability.

Scientific Applications:

  • Plasmid and Chromosome Visualization: Visualizes plasmid structures and genetic elements within circular bacterial genomes of Escherichia coli.
  • Comparative Genomics: Facilitates comparison of genomic features across different Escherichia coli strains or isolates.
  • Functional Genomics Mapping: Maps gene expression and other functional genomics data onto the E. coli genome.

Methodology:

Implemented in the R statistical programming language and leverages Bioconductor packages for plotting and statistical/computational analyses, with packages subject to Bioconductor's formal review and automated testing.

Topics

Collections

Details

License:
GPL-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

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