Ensembl Genomes

Ensembl Genomes provides integrated genomic annotations and comparative data for non-vertebrate species to support comparative and functional genomics studies.

Key Features:

• Extensive Genome Coverage: Includes over 23,000 bacterial genomes, 400 fungal genomes, 100 protist genomes, 55 invertebrate metazoan genomes, and 39 plant genomes.
• Data Integration: Integrates archival genome sequences, RNA sequence data, and variant calls within the context of reference genomes through automated processes.
• Polyploid Genome Analysis: Provides analyses and visual representations for polyploid genomes, exemplified by bread wheat.
• Annotation and Comparative Analyses: Contains curated gene models, transcriptional data, genetic variation, and comparative genomics analyses across non-vertebrate species.

Scientific Applications:

• Evolutionary Biology: Enables comparative genomics studies across diverse non-vertebrate taxa to investigate evolutionary relationships.
• Functional Genomics: Supports analysis of gene function and transcriptional regulation using gene models and RNA-seq data.
• Genetic Variation Analysis: Facilitates exploration of variant calls and population- or strain-level genetic variation.
• Biodiversity and Crop Genomics: Supports biodiversity assessments and analysis of complex crop genomes, including polyploid species like bread wheat.

Methodology:

Automated integration of archival genomic data; curation and annotation of genome sequences; development of gene models; incorporation of transcriptional (RNA-seq) and variant data; and a scalable architecture to accommodate increasing genomic datasets.