Ensembl Genomes Metazoa assembly converter

Ensembl Genomes Metazoa assembly converter maps genomic data between assemblies to project annotations, variants, and regulatory information onto current genome assemblies for Metazoa species.

Key Features:

• Comprehensive Species Coverage: Supports data from 87 species across main and early access platforms.
• Integration with Latest Assemblies: Provides updates for human, mouse, zebrafish, and rat assemblies and maintains compatibility with previous assemblies such as GRCh37.
• Genome Annotation and Analysis: Facilitates projection and analysis of genome annotations across assemblies.
• Enhanced Data Integration: Integrates third-party datasets and tools such as the Variant Effect Predictor (VEP) to enrich annotations.
• Scalable Analysis Capabilities: Uses RESTful APIs to enable large-scale and high-throughput analyses.
• Regulatory Data Access: BioMart provides rapid access to regulatory datasets.
• Visualization of Long-Range Interactions: Supports visualization of long-range interactions in cis-regulated datasets.

Scientific Applications:

• Genomic Annotation: Annotating genomes with up-to-date assemblies and projected annotations.
• Comparative Genomics: Mapping data across assemblies to perform comparative analyses between species.
• Variant Analysis: Analyzing genetic variants using integrated tools such as VEP to assess potential functional impacts.
• Regulatory Studies: Exploring regulatory datasets and long-range interactions to study gene regulation and expression patterns.

Methodology:

Maps data onto current genome assemblies, leverages RESTful APIs for scalable analysis, and integrates third-party datasets to enhance annotation capabilities.