Ensembl Genomes Protists assembly converter

Ensembl Genomes Protists assembly converter converts genomic coordinates and annotations between assembly versions for protist genomes to align datasets to current assemblies for accurate comparative and functional genomic analyses.

Key Features:

• Data Mapping Across Assemblies: Maps genomic data and annotations onto current genome assemblies to update coordinates between assembly versions.
• Integration with Latest Genome Assemblies: Supports current assemblies across a range of species including protists and maintains compatibility with previous releases such as GRCh37 and assemblies for human, mouse, zebrafish, and rat.
• Enhanced Data Integration: Incorporates additional third-party datasets to enrich genomic context and annotation.
• Scalable Analysis via RESTful APIs: Exposes functionality through RESTful APIs to support large-scale programmatic analyses.
• Regulatory Data Access via BioMart: Provides access to regulatory datasets through BioMart for retrieval of regulatory features.
• Visualization of Long-Range Interactions: Supports representation of long-range genomic interactions, including cis-regulated datasets.

Scientific Applications:

• Comparative Genomics: Enables comparative analyses by mapping data from different protist species or between protists and other organisms onto consistent assemblies.
• Functional Genomics: Facilitates identification and contextualization of functional elements by integrating regulatory data and long-range interaction information.
• Evolutionary Studies: Supports phylogenetic and evolutionary analyses by aligning datasets to up-to-date assemblies for accurate evolutionary inference.

Methodology:

Data mapping algorithms are used to map user data onto updated genome assemblies, and the tool integrates diverse third-party datasets.