Ensembl Rat Genome Browser

Ensembl Rat Genome Browser provides annotated Rattus norvegicus genome sequences within the Ensembl database, integrating stable automatic annotation and external datasets to support comparative and functional genomics.

Key Features:

• Comprehensive annotation: Provides stable, automatic annotation of the Rattus norvegicus genome that incorporates confirmed gene predictions.
• Integration of gene predictions and external datasets: Integrates gene predictions with external data sources to consolidate evidence for gene models and annotations.
• Data storage and visualization: Manages organization, storage, and visualization of large genomic sequences within the Ensembl framework.

Scientific Applications:

• Gene prediction validation: Validates and refines gene predictions for Rattus norvegicus by integrating multiple evidence sources.
• Comparative genomics: Enables comparative genomics analyses between rat and other species using integrated genome annotations from Ensembl.
• Functional annotation studies: Facilitates functional annotation by linking gene models to external datasets and annotations.
• Disease and evolutionary investigations: Supports investigation of evolutionary relationships and identification of potential genetic underpinnings of disease using integrated genomic annotations.

Methodology:

Genome sequencing, stable automatic annotation, integration of gene predictions with external datasets, and computational organization, storage, and visualization of large genomic sequences within the Ensembl framework.