Enzyme Portal

Enzyme Portal integrates publicly available enzyme-related data to provide consolidated information on small-molecule chemistry, biochemical pathways, drug compounds, disease associations, 3D protein structures, and scientific literature for studies of enzymatic function.


Key Features:

  • Integrated Data Access: Aggregates and retrieves enzyme-related information for proteins with enzymatic activity from various public repositories.
  • Supported Data Types: Provides access to small-molecule chemistry, biochemical pathways, drug compounds, disease information, 3D protein structures, and scientific literature.
  • Biochemical Reaction Information: Includes detailed biochemical reaction information related to enzymes.
  • Drug and Disease Associations: Links enzymes to potential drug compounds and related disease information.
  • Structural Data: Provides access to 3D protein structures for structural analysis and modeling.
  • Literature Linkage: Collates relevant scientific literature references associated with enzymes.

Scientific Applications:

  • Enzymatic Activity Research: Supports study of enzyme function by supplying biochemical reaction data and protein activity records.
  • Pathway Analysis: Assists exploration of biological pathways involving specific enzymes through integrated pathway data.
  • Drug Discovery: Aids identification and analysis of potential drug compounds and their interactions with enzymes.
  • Structural Biology: Enables structural analysis and modeling by providing 3D protein structure information.

Methodology:

No computational methods, algorithms, or processing pipelines are specified in the provided description.

Topics

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
6/11/2015
Last Updated:
11/25/2024

Operations

Publications

de Matos P, Cham JA, Cao H, Alcántara R, Rowland F, Lopez R, Steinbeck C. The Enzyme Portal: a case study in applying user-centred design methods in bioinformatics. BMC Bioinformatics. 2013;14(1). doi:10.1186/1471-2105-14-103. PMID:23514033. PMCID:PMC3623738.

Documentation