EpiMetal
EpiMetal performs integrated statistical analyses and data-driven metabolic profiling for epidemiology and metabolomics research.
Key Features:
- Standard epidemiological analyses: Supports standard epidemiological statistical analyses for cohort-level studies.
- Self-organizing maps: Uses self-organizing maps for data-driven metabolic profiling.
- Flexible data integration: Handles multiple large datasets containing arbitrary numbers of continuous and categorical variables.
- Statistical analysis and visualization: Integrates statistical analysis and visualization capabilities for exploration of high-dimensional molecular data.
Scientific Applications:
- Metabolomic profiling: Applied to datasets with over 500 quantitative molecular measures per sample for metabolic phenotyping.
- Epidemiological cohort analysis: Demonstrated in large-scale epidemiological cohorts with more than 10,000 participants for population-level analyses.
Methodology:
Implements standard epidemiological statistical analyses, self-organizing maps for data-driven metabolic profiling, and integrated statistical analysis and visualization.
Topics
Details
- License:
- MIT
- Tool Type:
- web application
- Programming Languages:
- JavaScript, Python
- Added:
- 1/18/2021
- Last Updated:
- 3/8/2021
Operations
Publications
Ekholm J, Ohukainen P, Kangas AJ, Kettunen J, Wang Q, Karsikas M, Khan AA, Kingwell BA, Kähönen M, Lehtimäki T, Raitakari OT, Järvelin M, Meikle PJ, Ala-Korpela M. EpiMetal: an open-source graphical web browser tool for easy statistical analyses in epidemiology and metabolomics. International Journal of Epidemiology. 2020;49(4):1075-1081. doi:10.1093/ije/dyz244. PMID:31943015. PMCID:PMC7660139.
DOI: 10.1093/IJE/DYZ244
PMID: 31943015
PMCID: PMC7660139
Funding: - NHMRC: APP1158958
- UK Medical Research Council: MC_UU_12013/1
- Novo Nordisk Foundation: NNF17OC0027034
Links
Repository
https://github.com/amergin/epimetal