EuroCarbDB

EuroCarbDB provides a relational repository of glycan and carbohydrate structures together with associated experimental data to support glycobiology and glycomics research.


Key Features:

  • Relational Database: Stores glycan/carbohydrate structures and their biological contexts in a relational schema.
  • Experimental Data Integration: Includes primary and interpreted analytical data from high-performance liquid chromatography (HPLC), mass spectrometry (MS), and nuclear magnetic resonance (NMR).
  • Glycoinformatics Tools: Provides tools for elucidation and submission of glycan structures and associated experimental data.
  • Biological Context Annotation: Associates structural entries with biological context information to link glycans to their sources or roles.
  • Open-source Licensing: Software and source code are licensed under the Lesser General Public License (LGPL).

Scientific Applications:

  • Structure Elucidation and Validation: Support elucidation and validation of glycan structures using integrated HPLC, MS, and NMR evidence.
  • Integrated Glycomics Analysis: Enable integration of structural and experimental data for comprehensive glycomics interpretation.
  • Data Submission and Curation: Facilitate submission and curation of glycan structures and analytical datasets for glycobiology research.

Methodology:

Data are organized in a relational database and integrated with primary and interpreted HPLC, MS, and NMR datasets, with glycoinformatics tools supporting structure elucidation and data submission.

Topics

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
Java
Added:
4/25/2017
Last Updated:
12/10/2018

Operations

Publications

von der Lieth C, Freire AA, Blank D, Campbell MP, Ceroni A, Damerell DR, Dell A, Dwek RA, Ernst B, Fogh R, Frank M, Geyer H, Geyer R, Harrison MJ, Henrick K, Herget S, Hull WE, Ionides J, Joshi HJ, Kamerling JP, Leeflang BR, Lutteke T, Lundborg M, Maass K, Merry A, Ranzinger R, Rosen J, Royle L, Rudd PM, Schloissnig S, Stenutz R, Vranken WF, Widmalm G, Haslam SM. EUROCarbDB: An open-access platform for glycoinformatics. Glycobiology. 2010;21(4):493-502. doi:10.1093/glycob/cwq188. PMID:21106561. PMCID:PMC3055595.

Documentation