EV Antibody Database

The EV Antibody Database aggregates and shares antibody validation results for extracellular vesicle and extracellular nanoparticle research to minimize wasted personnel time and reagents.

Key Features:

• Antibody Records: The database holds 110 records contributed by 6 laboratories from the Extracellular RNA Communication Consortium.
• Assay Modules: The database includes modules for antibodies tested for western Blot, EV Flow Cytometry, and EV Sandwich Assays.
• Detailed Validation Data: The database provides detailed information on antibody sources, assay conditions, and results, including negative findings.
• Community Input: The database encourages ongoing expert input and community feedback to enhance its utility.

Scientific Applications:

• EV Identification: Researchers use antibodies catalogued in the database for identification of extracellular vesicles and other extracellular nanoparticles.
• EV Characterization: Researchers use antibodies catalogued in the database for characterization of extracellular vesicles and other extracellular nanoparticles.
• EV Isolation: Researchers use antibodies catalogued in the database for isolation of extracellular vesicles and other extracellular nanoparticles.
• Protocol Optimization: Researchers access detailed assay variables and protocols to account for antibody performance variation among assay types and conditions.

Methodology:

The database was developed by investigators of the Extracellular RNA Communication Consortium and is hosted by the ExRNA Portal.