EVICAN

EVICAN provides a curated dataset for training and evaluating deep learning models for cell and nucleus segmentation from microscopy images.


Key Features:

  • Diverse Image Collection: 4,600 grayscale images from 30 different cell lines captured with various microscopes, contrast mechanisms, and magnifications.
  • Annotated Segmentations: Approximately 26,000 segmented cells annotated for segmentation tasks.
  • Brightfield Imaging Coverage: Images include brightfield microscopy suitable for automated cell and nucleus segmentation.

Scientific Applications:

  • Deep learning training and evaluation: Use as training and validation data for cell and nucleus segmentation algorithms, including Mask R-CNN.
  • Quantitative image analysis: Develop automated segmentation workflows for studies in cancer research, developmental biology, and drug discovery.

Methodology:

The dataset was used with a Mask R-CNN implementation, achieving a mean average precision (mAP) of 61.6% with a Jaccard Index above 0.5.

Topics

Details

License:
MIT
Tool Type:
command-line tool
Programming Languages:
Python, R
Added:
1/18/2021
Last Updated:
3/8/2021

Operations

Publications

Schwendy M, Unger RE, Parekh SH. EVICAN—a balanced dataset for algorithm development in cell and nucleus segmentation. Bioinformatics. 2020;36(12):3863-3870. doi:10.1093/bioinformatics/btaa225. PMID:32239126. PMCID:PMC7320615.

PMID: 32239126
PMCID: PMC7320615
Funding: - Welch Foundation: F-2008-20190330 - Human Frontiers in Science Program: RGP0045/2018