EVICAN
EVICAN provides a curated dataset for training and evaluating deep learning models for cell and nucleus segmentation from microscopy images.
Key Features:
- Diverse Image Collection: 4,600 grayscale images from 30 different cell lines captured with various microscopes, contrast mechanisms, and magnifications.
- Annotated Segmentations: Approximately 26,000 segmented cells annotated for segmentation tasks.
- Brightfield Imaging Coverage: Images include brightfield microscopy suitable for automated cell and nucleus segmentation.
Scientific Applications:
- Deep learning training and evaluation: Use as training and validation data for cell and nucleus segmentation algorithms, including Mask R-CNN.
- Quantitative image analysis: Develop automated segmentation workflows for studies in cancer research, developmental biology, and drug discovery.
Methodology:
The dataset was used with a Mask R-CNN implementation, achieving a mean average precision (mAP) of 61.6% with a Jaccard Index above 0.5.
Topics
Details
- License:
- MIT
- Tool Type:
- command-line tool
- Programming Languages:
- Python, R
- Added:
- 1/18/2021
- Last Updated:
- 3/8/2021
Operations
Publications
Schwendy M, Unger RE, Parekh SH. EVICAN—a balanced dataset for algorithm development in cell and nucleus segmentation. Bioinformatics. 2020;36(12):3863-3870. doi:10.1093/bioinformatics/btaa225. PMID:32239126. PMCID:PMC7320615.
PMID: 32239126
PMCID: PMC7320615
Funding: - Welch Foundation: F-2008-20190330
- Human Frontiers in Science Program: RGP0045/2018