EVPsort

EVPsort profiles and sorts small non-coding RNAs within extracellular vesicles and particles, integrating multiple databases and tools to investigate RNA-binding proteins and downstream functional effects.

Key Features:

• ncRNA Profiling: Provides an extensive overview of ncRNA profiling in 3,162 samples across various biofluids, cell lines, and disease contexts.
• Database Integration: Seamlessly integrates 19 external databases and tools encompassing information on associations between ncRNAs and RNA-binding proteins, motifs, targets, pathways, diseases, and drugs.
• Sorting Analysis: Extends profiling capabilities to investigate ncRNA sorting, identify relevant RNA-binding proteins and motifs, and assess functional implications.

Scientific Applications:

• EVP Communication Research: Supports investigation of cell-to-cell communication mediated by extracellular vesicles and particles through small non-coding RNA transport.
• Clinical Translation: Advances clinical applications by enabling thorough investigation into the abundance and sorting mechanisms of ncRNA within extracellular vesicles and particles.
• Functional Analysis: Facilitates assessment of downstream functional effects of ncRNAs through integrated RNA-binding protein and pathway information.

Methodology:

EVPsort integrates 19 external databases and tools to provide comprehensive ncRNA profiling and sorting analysis in extracellular vesicles and particles.