FAANG Data Portal

FAANG Data Portal provides centralized aggregation and organization of sample, sequencing, and analysis data from standardized multi-omic assays to enable functional annotation and comparative genomics of farmed and companion animal genomes.


Key Features:

  • Data aggregation: Aggregates and organizes sample, sequencing, and analysis data produced by FAANG consortia.
  • Multi-omic assay support: Houses standardized multi-omic assay datasets for functional genome annotation.
  • Metadata validation and brokering: Performs metadata validation and brokering services to ensure submissions meet EMBL-EBI archive standards.
  • Predictive search and filters: Provides predefined filters and predictive search capabilities for dataset discovery.
  • Protocol catalogue: Maintains a detailed catalogue of sampling and analysis protocols.
  • Publication linking: Automatically links datasets with associated publications.
  • FAIR compliance: Implements Findable, Accessible, Interoperable, and Reusable (FAIR) data management principles.
  • Scalability for emerging technologies: Plans to expand infrastructure to support single-cellomics, cell atlases, pangenomes, and phenotypic prediction models.
  • Governance and curation: Governed and curated by the FAANG Data Coordination Centre at the European Bioinformatics Institute (EMBL-EBI).

Scientific Applications:

  • Comparative genomics: Enables comparative analyses across terrestrial and aquatic animal species.
  • Functional element annotation: Supports identification and annotation of functional genomic elements in farmed and companion animals.
  • Agricultural improvement: Supports research aimed at improving farmed animal production, disease resistance, and genetic diversity.
  • Integration of emerging data types: Facilitates incorporation of single-cellomics, cell atlas, pangenome, and phenotypic prediction model data into functional studies.

Methodology:

Aggregates and organizes FAANG consortia data, applies metadata validation and brokering for EMBL-EBI archives, implements predefined filters and predictive search for discovery, and automatically links datasets to publications.

Topics

Details

Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Added:
11/28/2021
Last Updated:
11/28/2021

Operations

Publications

Harrison PW, Sokolov A, Nayak A, Fan J, Zerbino D, Cochrane G, Flicek P. The FAANG Data Portal: Global, Open-Access, “FAIR”, and Richly Validated Genotype to Phenotype Data for High-Quality Functional Annotation of Animal Genomes. Frontiers in Genetics. 2021;12. doi:10.3389/fgene.2021.639238. PMID:34220930. PMCID:PMC8248360.

PMID: 34220930
PMCID: PMC8248360
Funding: - Biotechnology and Biological Sciences Research Council: BB/N019202/1, BB/N019563/1 - Horizon 2020: 815668, 817923, 817998

Links