FASTA online toolbox

FASTA online toolbox provides utilities to manipulate FASTA sequences and to prepare formatted inputs for population genetics programs such as Arlequin, TCS, and MrBayes.

Key Features:

• Header manipulation: Extracts, edits, and replaces sequence headers in FASTA files for dataset organization.
• Dataset joining and splitting: Joins or divides datasets based on header information.
• Haplotype collapsing: Collapses identical sequences into haplotypes for downstream genetic analyses.
• Automated file formatting: Prepares input files formatted for Arlequin, TCS, and MrBayes.

Scientific Applications:

• Population genetics data preparation: Produces properly formatted inputs for population genetics programs including Arlequin, TCS, and MrBayes.
• Haplotype analysis: Enables collapse of sequences into haplotypes to assess genetic variation within populations.
• Sequence dataset management: Supports dataset organization and subset creation through header editing and dataset joining/splitting.

Methodology:

Header extraction, editing and replacement; dataset joining and splitting based on header information; sequence collapsing into haplotypes; automated formatting of files for Arlequin, TCS, and MrBayes.