FasParser2

FasParser2 performs batch manipulation of biological sequences and multiple sequence alignments to trim poorly-aligned regions, filter low-quality sequences, edit sequences, and interface with external programs for detection of positive selection and primer design.


Key Features:

  • Batch Processing: Supports batch operations on large sets of sequences and alignments.
  • Trimming Functionality: Strips poorly-aligned regions from multiple sequence alignments.
  • Sequence Quality Control: Identifies and removes sequences that are too short or excessively divergent.
  • Editor Tool: Provides sequence viewing and editing capabilities.
  • Integration with External Programs: Interfaces with other software to enable detection of positive selection and primer design.

Scientific Applications:

  • Comparative Genomics: Prepares and filters alignments for comparative analyses across genomes.
  • Evolutionary Studies: Processes datasets for analyses of divergence and evolutionary relationships.
  • Detection of Positive Selection: Supports workflows that identify selective pressures by interfacing with detection tools.
  • Primer Design: Integrates with programs used to design primers from curated sequence data.
  • Large-scale Sequence Data Processing: Enables management and preprocessing of extensive sequence datasets for downstream analyses.

Methodology:

Performs batch processing of sequences and alignments; trims poorly-aligned regions from multiple sequence alignments; identifies and removes sequences that are too short or excessively divergent; provides sequence viewing and editing; and interfaces with external programs for detection of positive selection and primer design.

Topics

Details

Tool Type:
command-line tool
Operating Systems:
Windows
Added:
7/1/2018
Last Updated:
11/25/2024

Operations

Publications

Sun Y. FasParser2: a graphical platform for batch manipulation of tremendous amount of sequence data. Bioinformatics. 2018;34(14):2493-2495. doi:10.1093/bioinformatics/bty126. PMID:29514176.

PMID: 29514176
Funding: - National Natural Science Foundation of China: 31671326 - Chinese Academy of Sciences: XDB13020200

Documentation