FermFooDb

FermFooDb catalogs 2,205 bioactive peptides derived from fermented foods and provides sequence, molecular mass, IC50 values, food source, functional activity, fermentation conditions including starter cultures, and experimental contexts (in vitro and in vivo) to support research into their nutritional and therapeutic properties.

Key Features:

• Dataset size: 2,205 peptide entries with annotated peptide sequence, molecular mass, IC50 values, food source, and specific functional activity.
• Diverse fermentation sources: Peptides originate from fermented foods including milk, cheese, yogurt, wheat, and rice.
• Functional activities: Recorded activities include antihypertensive, ACE-inhibitory, antioxidant, antimicrobial, immunomodulatory, and cholesterol-lowering effects.
• Fermentation details: Entries include fermentation conditions such as starter cultures and testing environments specified as in vitro and in vivo.
• Computational tools: Provides peptide mapping, similarity searches, and multiple-sequence alignments for sequence-level analyses.

Scientific Applications:

• Peptide discovery: Identify novel bioactive peptides and characterize their activities such as ACE inhibition and antioxidant effects.
• Functional food development: Link peptides to food sources and fermentation conditions to guide optimization of fermentation processes and product formulation.
• Nutrition and health research: Support studies in nutrition science, food technology, and health-related fields using sequence, IC50, and experimental-context data.

Methodology:

Peptide mapping of proteins, similarity searches, and multiple-sequence alignments are provided as the computational methods.