First Person Bioimage

First Person Bioimage provides immersive, GPU-accelerated visualization and interactive exploration of terascale 3D volumetric bioimaging datasets to enable direct volumetric navigation and inspection for analysis and interpretation.


Key Features:

  • Supported modalities: Handles terascale 3D datasets from SPIM, 3D STORM, OPT, tomographic EM, MRI, and CT.
  • GPU-accelerated rendering: Uses GPU-accelerated rendering capabilities available in contemporary browsers to enable responsive visualization.
  • Volumetric rendering: Provides full-volume volumetric rendering rather than curated static snapshots or videos.
  • First-person navigation: Implements a first-person navigation metaphor for spatial traversal and contextualization of structures within volumes.
  • Interactive exploration and manipulation: Supports real-time interactive navigation and data manipulation of large volumetric datasets.
  • Reproducibility and transparency: Enables direct access to complete volumetric data to facilitate transparent research communication and collaborative interpretation.

Scientific Applications:

  • Visualization of large-scale datasets: Visual inspection and exploration of terascale 3D bioimaging data across SPIM, 3D STORM, OPT, tomographic EM, MRI, and CT modalities.
  • Structural interpretation: Contextualization and inspection of fine structural details within full-volume biological specimens.
  • Reproducible data sharing: Support for transparent presentation and reuse of complete volumetric microscopy datasets to aid reproducibility.
  • Collaborative analysis: Facilitation of collaborative interpretation and comparative analysis of volumetric imaging experiments.

Methodology:

Implements browser-based GPU-accelerated volumetric rendering and real-time interactive navigation using a first-person navigation metaphor to provide full-volume access and manipulation of terascale 3D datasets.

Topics

Details

License:
CC-BY-NC-SA-4.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
Java, Python
Added:
8/23/2018
Last Updated:
6/16/2020

Operations

Publications

Fantham M, Kaminski CF. First Person Bioimage: An Online Tool for Presentation and Publication of Volumetric Data. Biophysical Journal. 2017;112(3):583a. doi:10.1016/j.bpj.2016.11.3139.

Documentation

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