FISH Oracle

FISH Oracle provides interactive visualization and integration of downstream-processed genomics data to analyze molecular alterations in cancer.

Key Features:

• Interactive Visualization: A search interface combined with a fast visualization engine enables highly interactive exploration of genomic events in processed datasets.
• Data Integration and Administration: Support for storing, selecting, and visualizing extensive volumes of downstream-processed genomics data facilitates management of large processed datasets.
• High-Quality Image Export: Visualizations can be exported into various high-quality image formats for presentation and analysis.
• Application in Cancer Research: Applied to published datasets, FISH Oracle revealed dual inactivation mechanisms of the gene TTC28 in colorectal cancer cells.

Scientific Applications:

• Cancer genomics visualization: Exploration and overview of complex patterns of molecular alterations in cancer cells using integrated downstream-processed genomics data.
• Hypothesis generation and investigation: Visualization and selection of large processed genomics datasets to support hypothesis formulation and follow-up analysis.
• Discovery of genomic alterations: Identification and characterization of events such as the dual inactivation of TTC28 in colorectal cancer.

Methodology:

Integration and visualization of downstream-processed genomics data using a search interface and a fast visualization engine, with support for exporting visualizations to high-quality image formats.