Fitchi

Fitchi generates haplotype genealogy graphs to visualize population genetic structure and phylogeographic relationships from sequence alignments.

Key Features:

• Graphical Representation: Produces haplotype genealogy graphs with node sizes proportional to haplotype frequencies.
• Edge Lengths: Calculates edge lengths that represent the minimum number of mutations separating adjacent haplotypes.
• Fitch Algorithm Utilization: Employs the Fitch algorithm to construct haplotype genealogy graphs.

Scientific Applications:

• Population Structure Analysis: Visualizes haplotype distributions and frequencies to support inference of population structure and dynamics.
• Phylogeographic Studies: Aids tracing the geographical distribution of genetic lineages to inform historical migration patterns and evolutionary processes.

Methodology:

Processes alignment files in Nexus format and applies the Fitch algorithm to construct haplotype genealogy graphs.