fobitoolsGUI

fobitoolsGUI provides access to the Food-Biomarker Ontology (FOBI) to perform food enrichment analyses, automatically annotate free-text dietary data, and visualize FOBI networks for nutrimetabolomic studies.


Key Features:

  • FOBI integration: Uses the Food-Biomarker Ontology (FOBI) as the structured reference for analyses and annotations.
  • Food enrichment analysis: Performs enrichment analyses to identify overrepresented food-related ontology terms in nutrimetabolomic datasets.
  • Network visualization: Visualizes FOBI networks to represent relationships between foods and biomarkers.
  • Automatic annotation of free-text dietary data: Maps unstructured dietary text to structured FOBI ontology terms.

Scientific Applications:

  • Nutrimetabolomic research: Supports studies of diet–metabolism interactions using ontology-based enrichment and network analyses.
  • Dietary pattern analysis: Enables identification and interpretation of food-related patterns within metabolomic datasets.
  • Biomarker discovery and interpretation: Facilitates detection and contextualization of potential dietary biomarkers and their metabolic implications.

Methodology:

Leverages the FOBI ontology to conduct enrichment analyses, visualize data networks, and map free-text dietary entries to FOBI terms via functions that interact with FOBI's structured data.

Topics

Details

License:
GPL-3.0
Cost:
Free of charge
Tool Type:
library
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
5/8/2022
Last Updated:
5/8/2022

Operations

Publications

Castellano-Escuder P, Andrés-Lacueva C, Sánchez-Pla A. The fobitools framework: the first steps towards food enrichment analysis. Bioinformatics. 2021;37(21):3969-3971. doi:10.1093/bioinformatics/btab626. PMID:34601570.

PMID: 34601570
Funding: - MINECO: PCIN2017-076 - ERA-Net Cofund on Intestinal Microbiomics: AC19 00096, AC19 00111 - ICREA: 2017SGR1546

Links