ForeStatistics

ForeStatistics performs statistical calculations for forensic DNA analysis, paternity testing, and relationship assessment by quantifying random match probabilities, combined probability of inclusion, and paternity indices.

Key Features:

• DNA Statistical Calculations: Computes random match probabilities for single-source profiles and combined probability of inclusion for mixed profiles.
• Profile Management and Matching: Performs profile matching for single-source and mixed profiles to support comparison and identification.
• Paternity and Relationship Testing: Calculates paternity indices for duo and trio cases, evaluates paternity when an alleged father is related to the mother or biological father, and assesses grandparents/grandchildren, avuncular (aunt/uncle–niece/nephew), and cousin relationships.
• Validation: Has undergone validation protocols confirming accuracy in DNA statistical calculations and profile matching.

Scientific Applications:

• Forensic casework: Provides quantified DNA evidence for criminal and civil investigations to support identification and kinship conclusions.
• Legal decision-making: Supplies statistical probabilities and relationship indices used in paternity, kinship, and other legal determinations, reducing manual calculation error and processing time.

Methodology:

Uses computer-aided calculations of random match probabilities, combined probability of inclusion, paternity indices (duo and trio), and profile matching, and has been evaluated via validation protocols.