FrameXplore

FrameXplore is a Google Colab notebook that extends ColabFold to automatically identify and correct disulfide bonds in cysteine‑rich protein structures. After a standard ColabFold prediction, it extracts all cysteine residues, computes Cα–Cα and S–S distances, identifies true disulfide bonds using geometric cutoffs (Cα–Cα < 6.5 Å, S–S < 2.5 Å), writes a corrected PDB with proper CONECT records, and provides an interactive 3D view.

Topics

Details

License:
MIT
Maturity:
Emerging
Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Linux, Mac, Windows
Programming Languages:
Python
Added:
5/13/2026
Last Updated:
5/13/2026

Operations

Publications

Documentation

General
https://github.com/Vidhusv/FRAMEXPLORER/blob/main/README.md
Quick start guide, example test case, methodology explanation, citation, and repository contents

Downloads

Links

Repository
https://github.com/Vidhusv/FRAMEXPLORER
(GitHub repository with source code, documentation, and logo)
Issue tracker
https://github.com/Vidhusv/FRAMEXPLORER/issues
(Report bugs, suggest features, or ask questions)