freak
freak generates residue and base frequency tables and plots to quantify sequence composition in nucleotide and amino acid sequences.
Key Features:
- Residue/Base Frequency Analysis: Calculates counts and relative frequencies for residues or bases from input biological sequences.
- Table and Plot Generation: Formats frequency data into tabular outputs and graphical plots for downstream analysis.
- EMBOSS Integration: Operates within the EMBOSS suite to interoperate with other EMBOSS applications and third-party software.
- Extensible C-based Implementation: Built on EMBOSS C programming libraries, enabling developer extension and customization.
- Scalability: Designed to handle large sequence datasets efficiently within the EMBOSS environment.
Scientific Applications:
- Sequence Analysis: Supports motif discovery and sequence comparison by providing residue and base frequency profiles.
- Data Visualization: Produces visual representations of sequence composition to aid interpretation and communication of results.
Methodology:
Analyzes input biological sequences to calculate per-residue or per-base frequencies, formats results as tables and graphical plots, and is implemented using EMBOSS C libraries for integration within the EMBOSS suite.
Topics
Collections
Details
- License:
- GPL-3.0
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- C
- Added:
- 11/8/2015
- Last Updated:
- 12/10/2018
Operations
Data Inputs & Outputs
Sequence composition calculation
Outputs
Publications
Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.
Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.
Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.