freak

freak generates residue and base frequency tables and plots to quantify sequence composition in nucleotide and amino acid sequences.


Key Features:

  • Residue/Base Frequency Analysis: Calculates counts and relative frequencies for residues or bases from input biological sequences.
  • Table and Plot Generation: Formats frequency data into tabular outputs and graphical plots for downstream analysis.
  • EMBOSS Integration: Operates within the EMBOSS suite to interoperate with other EMBOSS applications and third-party software.
  • Extensible C-based Implementation: Built on EMBOSS C programming libraries, enabling developer extension and customization.
  • Scalability: Designed to handle large sequence datasets efficiently within the EMBOSS environment.

Scientific Applications:

  • Sequence Analysis: Supports motif discovery and sequence comparison by providing residue and base frequency profiles.
  • Data Visualization: Produces visual representations of sequence composition to aid interpretation and communication of results.

Methodology:

Analyzes input biological sequences to calculate per-residue or per-base frequencies, formats results as tables and graphical plots, and is implemented using EMBOSS C libraries for integration within the EMBOSS suite.

Topics

Collections

Details

License:
GPL-3.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Windows, Mac
Programming Languages:
C
Added:
11/8/2015
Last Updated:
12/10/2018

Operations

Data Inputs & Outputs

Sequence composition calculation

Publications

Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.

Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.

Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.

Documentation

Downloads

Links