frogs_clusters_stat
frogs_clusters_stat computes statistical metrics and performs cluster-level analyses on high-throughput datasets, including next-generation DNA sequencing, to support genomic, transcriptomic, and proteomic investigations.
Key Features:
- Integration with Galaxy: Interoperates with the Galaxy framework for workflow execution and data exchange.
- Cluster metric computation and statistical evaluation: Computes metrics and performs statistical analyses on clusters derived from high-throughput data.
- Scalability for large-scale datasets: Supports processing and statistical evaluation of clusters from high-throughput sequencing (including next-generation DNA sequencing) and other large biomedical datasets.
- Automation and provenance recording: Automates analytical steps and records logs and provenance of operations.
Scientific Applications:
- Genomic Data Analysis: Processes clusters of genomic sequences to identify patterns and variations relevant to genetic disease and evolutionary biology.
- Transcriptomic Studies: Analyzes transcriptome cluster data to evaluate gene expression profiles across conditions or treatments.
- Proteomic Investigations: Applies cluster-level analyses to proteomic datasets to examine protein interactions and modifications at scale.
Methodology:
Uses advanced statistical techniques tailored for high-throughput data to compute cluster-level metrics and integrates with the Galaxy framework for workflow execution and data exchange.
Topics
Collections
Details
- Maturity:
- Mature
- Tool Type:
- web application
- Operating Systems:
- Linux, Windows, Mac
- Added:
- 12/19/2016
- Last Updated:
- 11/25/2024
Operations
Data Inputs & Outputs
Publications
Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.
Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.