frogs_clusters_stat

frogs_clusters_stat computes statistical metrics and performs cluster-level analyses on high-throughput datasets, including next-generation DNA sequencing, to support genomic, transcriptomic, and proteomic investigations.


Key Features:

  • Integration with Galaxy: Interoperates with the Galaxy framework for workflow execution and data exchange.
  • Cluster metric computation and statistical evaluation: Computes metrics and performs statistical analyses on clusters derived from high-throughput data.
  • Scalability for large-scale datasets: Supports processing and statistical evaluation of clusters from high-throughput sequencing (including next-generation DNA sequencing) and other large biomedical datasets.
  • Automation and provenance recording: Automates analytical steps and records logs and provenance of operations.

Scientific Applications:

  • Genomic Data Analysis: Processes clusters of genomic sequences to identify patterns and variations relevant to genetic disease and evolutionary biology.
  • Transcriptomic Studies: Analyzes transcriptome cluster data to evaluate gene expression profiles across conditions or treatments.
  • Proteomic Investigations: Applies cluster-level analyses to proteomic datasets to examine protein interactions and modifications at scale.

Methodology:

Uses advanced statistical techniques tailored for high-throughput data to compute cluster-level metrics and integrates with the Galaxy framework for workflow execution and data exchange.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
12/19/2016
Last Updated:
11/25/2024

Operations

Data Inputs & Outputs

Publications

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Documentation

Links