frogs_clusters_stat

frogs_clusters_stat computes statistical metrics and performs cluster-level analyses on high-throughput datasets, including next-generation DNA sequencing, to support genomic, transcriptomic, and proteomic investigations.


Key Features:

  • Integration with Galaxy: Interoperates with the Galaxy framework for workflow execution and data exchange.
  • Cluster metric computation and statistical evaluation: Computes metrics and performs statistical analyses on clusters derived from high-throughput data.
  • Scalability for large-scale datasets: Supports processing and statistical evaluation of clusters from high-throughput sequencing (including next-generation DNA sequencing) and other large biomedical datasets.
  • Automation and provenance recording: Automates analytical steps and records logs and provenance of operations.

Scientific Applications:

  • Genomic Data Analysis: Processes clusters of genomic sequences to identify patterns and variations relevant to genetic disease and evolutionary biology.
  • Transcriptomic Studies: Analyzes transcriptome cluster data to evaluate gene expression profiles across conditions or treatments.
  • Proteomic Investigations: Applies cluster-level analyses to proteomic datasets to examine protein interactions and modifications at scale.

Methodology:

Uses advanced statistical techniques tailored for high-throughput data to compute cluster-level metrics and integrates with the Galaxy framework for workflow execution and data exchange.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
12/19/2016
Last Updated:
11/25/2024

Operations

Data Inputs & Outputs

Clustering

Inputs

Outputs

Publications

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Documentation

Links