Fuento

Fuento performs functional enrichment analysis of gene expression data to identify enriched biological functions and pathways.

Key Features:

• Functional enrichment analysis: Performs enrichment analysis on gene expression datasets to detect overrepresented biological terms and pathways.
• Gene expression focus: Primarily targeted at analyses of gene expression data to derive functional insights.
• Multifunctional analyses: Supports a wide range of functional enrichment analyses across different annotation sets and categories.
• Implementation: Implemented in C++ and optimized for performance and flexibility.
• Platform support: Operates on Linux and OS X environments.

Scientific Applications:

• Gene function annotation: Infers functions of genes based on enrichment of annotated terms in expression-derived gene sets.
• Pathway and disease mechanism identification: Identifies pathways and biological processes potentially involved in disease mechanisms from expression data.
• Regulatory network exploration: Supports exploration of regulatory networks by linking expression changes to functional categories and pathways.

Methodology:

Performs computational functional enrichment analyses on gene expression datasets and is implemented in C++ optimized for performance and flexibility.