G-language Genome Analysis Environment WS

G-language Genome Analysis Environment WS provides web-service access to genome-analysis functions for computing nucleic acid composition, codon usage, genomic signatures, and related analyses on complete genome flatfiles and genome annotations.

Key Features:

• Web-service access (REST/SOAP): Provides REST and SOAP web services to invoke G-language Genome Analysis Environment functions on genome data.
• EMBOSS integration: Integrates with the European Molecular Biology Open Software Suite (EMBOSS) to enable combined analyses with EMBOSS programs.
• Analytical tools: Implements nucleic acid composition analysis, codon usage calculation, and genomic visualization applicable to meta-genomic and meta-transcriptomic datasets.
• Advanced analyses: Supports genomic-signature–based sequence distance calculations and codon-usage–based gene expression prediction for large-scale genomic datasets.
• Command-line compatibility: Functions can be used alongside UNIX command-line utilities and other EMBOSS programs.

Scientific Applications:

• Metagenomics and metatranscriptomics: Analysis of nucleic acid composition and codon usage in meta-genomic and meta-transcriptomic datasets.
• Gene expression inference: Prediction of gene expression levels from codon usage bias.
• Comparative genomics and evolutionary analysis: Assessing evolutionary relationships and sequence similarity using genomic signatures and distance calculations.
• Genome annotation analysis: Extraction of sequence- and codon-based metrics from complete genome flatfiles and genome annotations.

Methodology:

Invocation of G-language Genome Analysis Environment functions via REST and SOAP web services on complete genome flatfiles and annotations to perform nucleic acid composition analysis, codon usage calculation, genomic visualization, genomic-signature distance computation, and codon-usage–based gene expression prediction.