GAG

GAG generates NCBI-compatible annotation tables by converting and curating annotated whole genome sequencing (WGS) assemblies into the NCBI annotation table (.tbl) format for submission to the NCBI Genome Assembly database.


Key Features:

  • Conversion to .tbl: Converts annotated genome assemblies into the NCBI annotation table (.tbl) file format.
  • Annotation assessment: Performs assessment of annotations to identify issues requiring curation.
  • Post-annotation filtering: Applies post-annotation assembly filtering to select or remove features prior to submission.
  • Annotation transfer: Transfers annotations from assembly files into the .tbl structure required by NCBI.
  • NCBI compliance: Generates .tbl files aligned with the requirements of the NCBI Genome Assembly database.

Scientific Applications:

  • WGS submission preparation: Preparing whole genome sequencing (WGS) data and annotated assemblies for submission to the NCBI Genome Assembly database.
  • Assembly curation: Curation and standardization of annotated genome assemblies prior to repository deposition.
  • Post-annotation QC: Post-annotation quality control and filtering of assemblies in WGS projects.

Methodology:

Performs annotation assessment, post-annotation assembly filtering, transfer of annotations, and conversion of assemblies into the NCBI annotation table (.tbl) format.

Topics

Details

License:
MIT
Tool Type:
command-line tool
Operating Systems:
Linux, Windows, Mac
Programming Languages:
Python
Added:
7/13/2018
Last Updated:
11/24/2024

Operations

Publications

Geib SM, Hall B, Derego T, Bremer FT, Cannoles K, Sim SB. Genome Annotation Generator: a simple tool for generating and correcting WGS annotation tables for NCBI submission. GigaScience. 2018;7(4). doi:10.1093/gigascience/giy018. PMID:29635297. PMCID:PMC5887294.

Documentation