GameRank

GameRank optimizes feature selection for predictive modeling using a maximum likelihood-based algorithm and combinatorial search to produce calibrated and discriminative models for clinical risk stratification.


Key Features:

  • Maximum Likelihood-Based Feature Selection: Implements a maximum likelihood framework to identify features that improve model performance.
  • Combinatorial Search Optimization: Employs combinatorial search algorithms to efficiently navigate extensive feature-subset search spaces.
  • Calibrated and Discriminative Models: Targets construction of models that provide accurate class discrimination and reliable probability calibration.
  • Clinical Risk Identification: Enables identification of high-risk and low-risk patients for clinical applications.

Scientific Applications:

  • Clinical risk stratification: Supports identifying high-risk and low-risk patients in clinical settings where timely risk separation is critical.
  • High-dimensional feature selection: Applies to large datasets and complex feature spaces to select informative predictors.
  • Predictive model development: Facilitates building models that balance discrimination and calibration for reliable probability estimates.

Methodology:

GameRank integrates a maximum likelihood-based feature selection algorithm with combinatorial search techniques to optimize predictive model performance.

Topics

Details

License:
MIT
Cost:
Free of charge
Tool Type:
library
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
10/11/2022
Last Updated:
11/24/2024

Operations

Data Inputs & Outputs

Database search

Outputs

    Publications

    Henneges C, Paulson JN. GameRank: R package for feature selection and construction. Bioinformatics. 2022;38(20):4840-4842. doi:10.1093/bioinformatics/btac552. PMID:35951761. PMCID:PMC9563696.