gdtools_gd2gvf

gdtools_gd2gvf converts Genome Diff (GD) files into Genome Variation Format (GVF) files to represent and document genomic variations such as insertions, deletions, and substitutions for downstream variant analysis.


Key Features:

  • Conversion Capability: Converts GD files into GVF files that represent genomic variations including insertions, deletions, and substitutions.
  • Galaxy integration: Executes within the Galaxy platform and can be incorporated into Galaxy workflows via the Galaxy API or the Bioblend library.

Scientific Applications:

  • Genomic Variation Analysis: Produces GVF outputs suitable for analyses of genetic diversity, mutation annotation, and variant interpretation.
  • Metagenomics workflow integration: Provides standardized GVF-formatted mutation data that can be integrated with metagenomics analysis services such as MetaGenSense.

Methodology:

Processes GD files using the Galaxy execution engine and communicates with Galaxy via the Galaxy API or the Bioblend library.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
12/19/2016
Last Updated:
6/16/2020

Operations

Publications

Barrick JE, Colburn G, Deatherage DE, Traverse CC, Strand MD, Borges JJ, Knoester DB, Reba A, Meyer AG. Identifying structural variation in haploid microbial genomes from short-read resequencing data using breseq. BMC Genomics. 2014;15(1):1039. doi:10.1186/1471-2164-15-1039. PMID:25432719. PMCID:PMC4300727.

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Documentation

Links