gdtools_gd2gvf

gdtools_gd2gvf converts Genome Diff (GD) files into Genome Variation Format (GVF) files to represent and document genomic variations such as insertions, deletions, and substitutions for downstream variant analysis.


Key Features:

  • Conversion Capability: Converts GD files into GVF files that represent genomic variations including insertions, deletions, and substitutions.
  • Galaxy integration: Executes within the Galaxy platform and can be incorporated into Galaxy workflows via the Galaxy API or the Bioblend library.

Scientific Applications:

  • Genomic Variation Analysis: Produces GVF outputs suitable for analyses of genetic diversity, mutation annotation, and variant interpretation.
  • Metagenomics workflow integration: Provides standardized GVF-formatted mutation data that can be integrated with metagenomics analysis services such as MetaGenSense.

Methodology:

Processes GD files using the Galaxy execution engine and communicates with Galaxy via the Galaxy API or the Bioblend library.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
12/19/2016
Last Updated:
6/16/2020

Operations

Data Inputs & Outputs

Formatting

Inputs

Outputs

Publications

Barrick JE, Colburn G, Deatherage DE, Traverse CC, Strand MD, Borges JJ, Knoester DB, Reba A, Meyer AG. Identifying structural variation in haploid microbial genomes from short-read resequencing data using breseq. BMC Genomics. 2014;15(1):1039. doi:10.1186/1471-2164-15-1039. PMID:25432719. PMCID:PMC4300727.

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Documentation

Links