gdtools_not-evidence

gdtools_not-evidence filters GenomeDiff files to remove entries that are not used as evidence for mutations, producing a refined GenomeDiff focused on mutation-supporting records.

Key Features:

• Selective Filtering: Identifies and removes GenomeDiff entries that are not utilized as evidence for mutations.
• Output Customization: Writes the refined GenomeDiff to a specified output path or, if none is provided, emits a verbose report listing excluded entries.
• Integration with Galaxy Platform: Executes within the Galaxy platform as a Galaxy tool, enabling execution in Galaxy-managed workflows and on compute resources such as clusters at Institut Pasteur.
• Web Service Compatibility: Interacts with Galaxy via the Galaxy API or the Bioblend library to submit and manage computational tasks.

Scientific Applications:

• Genomic Research: Refines GenomeDiff files to focus analyses on mutation evidence for studies of genetic variation, disease association, and evolutionary biology.
• Data Management: Reduces non-contributory entries in GenomeDiff datasets to decrease storage and downstream computational load.

Methodology:

Parses GenomeDiff files to identify and remove entries that do not contribute to mutation evidence; runs as an automated Galaxy job and can provide verbose output when no explicit output path is specified; communicates with Galaxy via the Galaxy API or Bioblend.