GeMo

GeMo performs in silico chromosome painting to generate and curate genome ancestry mosaics for mapping genetic contributions and identifying hybridization events.

Key Features:

• In silico chromosome painting: generates chromosome-level ancestry mosaics to map genetic contributions from distinct groups.
• Ancestry mosaic curation: provides an interactive data curation mode to refine and verify automated ancestry calls.
• Recombination tracking: detects and tracks chromosomal recombinations occurring naturally or induced by selective breeding.
• Linear-based visualization: presents ancestry mosaics in a linear layout to enhance clarity and interpretability of chromosomal data.
• Scripted analytical workflow: includes a script that executes analytical commands to streamline data input generation.
• Preloaded published datasets: ships with datasets from published studies on crop domestication for immediate analysis.
• Cross-taxa applicability: adapts to analyses in both plant and animal studies, including breeding programs.

Scientific Applications:

• Hybrid formation analysis: elucidates mechanisms underlying hybrid formation by mapping group contributions across genomes.
• Hybridization detection: identifies contributing genetic groups and detects hybridization events in individuals and populations.
• Recombination and breeding studies: enables study of chromosomal recombinations from natural processes or selective breeding to assess genetic diversity and evolution.
• Crop domestication research: applies preloaded published datasets to investigate domestication histories and ancestry in crops.
• Animal genetics and breeding: supports application of ancestry mosaics and recombination tracking to animal studies and breeding programs.

Methodology:

Implements in silico chromosome painting with a script-executed analytical workflow, employs linear-based visualization, and supports interactive data curation.