genArise
genArise analyzes dual color microarray data to perform differential gene expression and comparative gene expression analyses using R and Bioconductor methodologies.
Key Features:
- Dual-color microarray support: Processes datasets generated from dual color microarray experiments for downstream analysis.
- Differential expression detection: Identifies differentially expressed genes from microarray data.
- Comparative expression analysis: Enables comparative studies between different biological conditions using microarray measurements.
- Developer extensibility: Provides tools for customization and extension of analytical capabilities.
- R/Bioconductor integration: Integrates the statistical programming language R and Bioconductor packages for high-throughput data analysis.
Scientific Applications:
- Gene expression analysis: Analysis of gene expression profiles obtained from dual color microarrays.
- Comparative studies: Comparison of expression patterns across different biological conditions or treatments.
- Differential expression studies: Detection and reporting of genes exhibiting expression changes between conditions.
- Genomics and molecular biology research: Application in genomics and molecular biology investigations that utilize microarray data.
Methodology:
Implemented in the statistical programming language R and aligned with Bioconductor methodologies, leveraging Bioconductor packages for microarray data analysis.
Topics
Collections
Details
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.