Genatlas

Genatlas catalogs gene structures, sequences, expression patterns, mutations, and functional annotations to support studies of developmental genetics and human disease.

Key Features:

• Gene Information: Extensive data on gene structures, including genetic sequences and functional annotations.
• Expression Data: Information on gene expression patterns across various tissues and developmental stages.
• Functional Insights: Detailed descriptions of gene functions involved in developmental processes, including extracellular signaling and target gene activation.

Scientific Applications:

• Developmental Genetics: Resource for studying developmental genes from embryonic stages through maturity, highlighting roles in extracellular signaling and target gene activation.
• Disease Association: Maps genes associated with congenital malformations and developmental anomalies, supporting analysis of genetic and phenotypic heterogeneity.

Methodology:

Ortholog mapping identifies human orthologs of genes previously characterized in lower species. Associative analysis links specific gene mutations to developmental anomalies to aid elucidation of disease mechanisms.