GenBase

GenBase archives, searches, and shares nucleotide sequences and associated annotations following International Nucleotide Sequence Database Collaboration (INSDC) data standards and structures.

Key Features:

• Bilingual submission pipeline: GenBase provides bilingual submission services and local submission assistance in China.
• Excel format for metadata: GenBase offers a unique Excel format for metadata description and feature annotation of nucleotide sequences.
• Real-time data validation: GenBase includes a real-time data validation system to streamline sequence submissions.
• Data access mechanisms: Released sequences are accessible through a web search system, File Transfer Protocol (FTP), and Application Programming Interface (API).
• INSDC data exchange: GenBase has constructed a data exchange mechanism with GenBank and shares released nucleotide sequences with INSDC.
• GenBank integration: GenBase integrates all sequences from GenBank with daily updates.

Scientific Applications:

• Nucleotide sequence archiving: GenBase archives nucleotide sequences and associated annotations for long-term preservation and access.
• Protein sequence annotation: GenBase stores and distributes annotated protein sequences derived from nucleotide submissions.
• Cross-database sequence sharing: GenBase enables global sequence data management and sharing through collaboration with GenBank and INSDC.

Methodology:

GenBase follows INSDC data standards and structures, employs a real-time data validation system for submissions, and constructs data exchange mechanisms with GenBank for sharing released nucleotide sequences.