GeneTEFlow

GeneTEFlow analyzes gene and locus-specific transposable element (TE) expression from RNA-Seq data for integrated studies of gene and TE regulation.


Key Features:

  • Reproducibility and platform independence: Uses Nextflow and Docker to provide reproducible execution across diverse computing environments.
  • Automated workflow: Implements a fully automated workflow that minimizes manual intervention during data processing.
  • Comprehensive analysis of genes and locus-specific transposable elements: Performs simultaneous analysis of gene expression and locus-specific TE expression from RNA-Seq datasets.

Scientific Applications:

  • Embryogenesis: Enables investigation of gene and TE expression dynamics during embryogenesis.
  • Neurodevelopment: Supports analysis of gene and TE regulation in neurodevelopmental processes.
  • Immune function: Facilitates study of gene and TE expression related to immune functions.
  • Human disease studies: Aids exploration of how gene and TE expression contribute to human diseases.

Methodology:

The pipeline uses Nextflow to orchestrate workflow execution and Docker containers to encapsulate software dependencies for analyzing gene and locus-specific TE expression from RNA-Seq data.

Topics

Details

Tool Type:
command-line tool
Programming Languages:
Python, R, Perl
Added:
1/18/2021
Last Updated:
1/22/2021

Operations

Publications

Liu X, Bienkowska JR, Zhong W. GeneTEFlow: A Nextflow-based pipeline for analysing gene and transposable elements expression from RNA-Seq data. Unknown Journal. 2020. doi:10.1101/2020.04.28.065862.