GeneTEFlow
GeneTEFlow analyzes gene and locus-specific transposable element (TE) expression from RNA-Seq data for integrated studies of gene and TE regulation.
Key Features:
- Reproducibility and platform independence: Uses Nextflow and Docker to provide reproducible execution across diverse computing environments.
- Automated workflow: Implements a fully automated workflow that minimizes manual intervention during data processing.
- Comprehensive analysis of genes and locus-specific transposable elements: Performs simultaneous analysis of gene expression and locus-specific TE expression from RNA-Seq datasets.
Scientific Applications:
- Embryogenesis: Enables investigation of gene and TE expression dynamics during embryogenesis.
- Neurodevelopment: Supports analysis of gene and TE regulation in neurodevelopmental processes.
- Immune function: Facilitates study of gene and TE expression related to immune functions.
- Human disease studies: Aids exploration of how gene and TE expression contribute to human diseases.
Methodology:
The pipeline uses Nextflow to orchestrate workflow execution and Docker containers to encapsulate software dependencies for analyzing gene and locus-specific TE expression from RNA-Seq data.
Topics
Details
- Tool Type:
- command-line tool
- Programming Languages:
- Python, R, Perl
- Added:
- 1/18/2021
- Last Updated:
- 1/22/2021
Operations
Publications
Liu X, Bienkowska JR, Zhong W. GeneTEFlow: A Nextflow-based pipeline for analysing gene and transposable elements expression from RNA-Seq data. Unknown Journal. 2020. doi:10.1101/2020.04.28.065862.