Genie
Genie simulates real-time population-genetic processes to illustrate neutral evolution, genetic drift, population isolation, gene flow, and genetic mutation for teaching and exploration of evolutionary dynamics.
Key Features:
- Interactive simulations: Provides real-time simulations that demonstrate genetic drift, population isolation, gene flow, and genetic mutation within populations.
- Variable manipulation: Enables manipulation of population-genetic variables to observe outcomes in simulated populations.
- Educational integration: Has been integrated into instructional settings to support teaching of evolutionary biology and to address misconceptions about non-adaptive evolutionary processes.
- Assessment and validation: Effectiveness was evaluated using the Genetic Drift Inventory (Price et al., CBE Life Sci Educ 13(1):65-75, 2014) and showed comparable performance to traditional static methods.
Scientific Applications:
- Instruction in evolutionary biology: Supports classroom and laboratory instruction focused on neutral evolution and genetic drift.
- Exploration of evolutionary forces: Allows investigation of how population isolation, gene flow, and mutation affect allele frequencies in simulated populations.
- Educational assessment: Can be used alongside standardized instruments such as the Genetic Drift Inventory to evaluate student understanding of genetic drift.
Methodology:
Real-time, interactive simulations permit manipulation of variables and observation of outcomes within simulated populations.
Topics
Details
- License:
- Not licensed
- Cost:
- Free of charge
- Tool Type:
- web application
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- R
- Added:
- 12/31/2022
- Last Updated:
- 11/24/2024
Operations
Data Inputs & Outputs
Allele frequency distribution analysis
Inputs
Outputs
Publications
Castillo AI, Roos BH, Rosenberg MS, Cartwright RA, Wilson MA. Genie: an interactive real-time simulation for teaching genetic drift. Evolution: Education and Outreach. 2022;15(1). doi:10.1186/s12052-022-00161-7. PMID:36237301. PMCID:PMC9555832.
PMID: 36237301
PMCID: PMC9555832
Funding: - National Science Foundation: DBI-1356548
- National Institute of General Medical Sciences: R35GM124827